Research Progress

[11-03-2016]New progress on self-assembly of ferritin nanoparticles

The self-assembly of nanoparticles into larger superstructures is a powerful strategy to develop novel functional nanomaterials, as these superstructures display collective properties that are different to those displayed by individual nanoparticles or bulk samples. However, there are increasing bottlenecks in terms of size control and multifunctionalization of nanoparticle assemblies.

[11-03-2016]Real-Time Tracking of the Fate of Protein Nanomedicine In Vivo

Protein nanocages (PNCs) have been recognized as a promising platform for nanomedicine innovation. Real-time in vivo tracking of PNCs can provide critically important information for the development of PNC-based diagnostics and therapeutics.

[11-03-2016]GPI Anchor Modification Machinery Deficiency Causes Accumulation of Pro-PrP in BxPC-3

On Dec 18, 2015, the research group led by Prof. Chaoyang Li in WIV, had reported the identification of another PDAC cell line, AsPC-1, which expresses a matured, GPI-anchoredPrP.Comparisonofthe24genes involved in the GPI anchor modification pathway between AsPC-1 and BxPC-3 revealed 15 of the 24 genes, including PGAP1 and PIG-F were down regulated in the latter cells. They also identified 6 mi...

[04-12-2015]New progress on treating inflammatory diseases

Inflammatory response plays significant roles in human body’s resistance outside pathogen invading, repair of tissue and adjustment of stress response. In pathology state, abnormal inflammatory response relates closely to a variety of diseases. Hepatocellular carcinoma (HCC) has become a major public health problem in China, which is frequently associated with pathogen infection–induced chron...