Research Progress

[01-08-2016]Scientists in WIV Observed the Sequential Disassembly Process of Single HIV-1 Virus Particles in ...

On June 2nd 2016, the study jointly developed by the research teams led by Professor Zongqiang Cui in WIV, Professor Xianen Zhang in Institute of Biophysics, CAS and Professor Zhike He in Wuhan University was published online by the ACS Nano journal. The research paper (DOI: 10.1021/acsnano.6b02462) first demonstrates the real-time imaging of single HIV-1 disassembly with multicolor viral parti...

[01-08-2016]WIV First Illustrated a Mechanism for σE in Response to Oxidative Stress through Regulation of r...

Mycobacterium tuberculosis adopts various strategies to cope with oxidative stress during infection. Transcriptional regulators, including σ factors, make important contributions to this stress response, but how these proteins cooperate with each other is largely unknown. In the study (DOI: 10.1111/mmi.13449), the role of RbpA and its cooperation with σ factors in response to oxidative stress...

[01-08-2016]Human Bocavirus NS1 and NS1-70 Proteins Inhibit TNF-α-Mediated Activation of NF-κB by targeting...

Human bocavirus (HBoV), a parvovirus, is a single-stranded DNA etiologic agent causing lower respiratory tract infections in young children worldwide. Nuclear factor kappa B (NF-κB) transcription factors play crucial roles in clearance of invading viruses through activation of many physiological processes. Previous investigation showed that HBoV infection could significantly upregulate the lev...

[02-06-2016]Scientist in WIV achieves a progress in study on reassortment of influenza viruses

Multiple infections of avian influenza viruses (AIVs) in poultry or wild birds contribute to the continued evolution of H5 subtype viruses in nature and provide potential recombination of AIVs of different origins. In this study, by collaboration with Prof. Qiyun Zhu in Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences and Prof. Hualan Chen in Harbin Veterinary Res...